CSIP: PRELIMS BOOSTER SERIES- 155 SCIENCE AND TECHNOLOGY
HEMOCHROMATOSIS
Hemochromatosis is a rare genetic disorder known for iron overload, leading to organ dysfunction.
Types of Hemochromatosis:
- There are two main types:
- Hereditary Hemochromatosis: This type results from an HFE gene mutation, causing individuals to absorb excessive iron from their diet.
- Secondary Hemochromatosis: Typically caused by external factors like frequent blood transfusions, iron supplements, or specific medical conditions.
- Hereditary Hemochromatosis Effects: Individuals with hereditary hemochromatosis gradually accumulate excess iron, affecting vital organs like the liver, heart, and pancreas, potentially leading to cirrhosis, heart failure, diabetes, and arthritis.
- Secondary Hemochromatosis Effects: accumulation in secondary hemochromatosis can be more rapid, causing organ dysfunction.
In summary, hemochromatosis is a genetic disorder that causes excessive iron absorption, potentially leading to severe organ problems in its hereditary and secondary forms.